专利名称：2H-(1) benzoxepino (5,4-b)-1,4 oxazine
derivatives
发明人：Freedman, Jules申请号：EP84101519.1申请日：19840214公开号：EP0116372A1公开日：19840822
摘要：Derivatives of 2H-[1]benzoxepino[5,4-b]-1,4-oxazine, such as (4a,11b)-3,4,4a,5,6,11b-hexahydro-2H-[1]benzoxepino[5,4-b]-1,4-oxazine, are prepared byacylating a 4-amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ol, cyclizing the resultingchloroacetamido alcohol, reducing the 1,4-oxazine-3(4H)-one so obtained, acylating theresulting 2H-[1]benzoxepino[5,4-b]-1,4-oxazine, and reducing the N-acyl-2H-[1]benzoxepino[5,4-b]-1,4-oxazine so obtained. The novel compounds disclosed hereinpossess useful muscle relaxant and analgesic properties.
申请人：MERRELL DOW PHARMACEUTICALS INC.
地址：2110 East Galbraith Road, P.O. Box 156300 Cincinnati Ohio 45215-6300 US
国籍：US
代理机构：VOSSIUS & PARTNER
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